GeneTex S100 beta antibody [EP1576Y], C-term

Кроличьи моноклональные антитела ДженТекс, выборка антител по технологии RMAb.

S100-β is a homodimeric member of the EF-hand calcium-binding protein superfamily. The protein has been implicated in cellular processes such as cell differentiation and growth, plays a role in cytoskeletal structure and function, and may have a role in neuropathological diseases, such as Alzheimers. The effects of S100-β are mediated via its interaction with target proteins . S100-β protein is a low molecular weight, EF-hand, Ca2(+)-binding protein widely distributed and conserved in the central nervous system of vertebrates . Measurements of Ca2+ binding to human brain S100-β (beta beta) protein revealed six Ca2+-binding sites and zinc-binding studies on human S100b protein showed that the protein bound two zinc ions per beta monomer. These results indicate that the Ca2+- and Zn2+-binding sites on S100-β protein are different and suggest that Zn2+ may regulate Ca2+ binding by increasing the affinity of the protein for calcium.

• Выборка антител, приготовленных по технологии RMAb
• Полный перечень антител GeneTex

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